Technical Service Need help? Our team of experienced experts is here for you with full support.
AKA-147
Sophocarpine
Cat. No.
AKA-147
CAS No.
6483-15-4
MF
C15H22N2O
MW
246.354
Sophocarpine is a PTEN activator and an inhibitor of PI3K/Akt, MEK/ERK and NF-κB signaling pathways.
Advanced Equipments & Extensive Production Expertise
Commercial Manufacturing
Stable Quality
Customization Supporting
Technical Service 
86-28-85159085 
info@aktin.com
Technical Data
Description
Storage and Shipping
References
Product Name
Sophocarpine
CAS No.
6483-15-4
MF
C15H22N2O
MW
246.354
Specification
98%
Description
Sophocarpine is a PTEN activator and an inhibitor of PI3K/Akt, MEK/ERK and NF-κB signaling pathways. Packing: 10mg, 20mg, 50mg, 100mg, 500mg, 1g, 5g, 10g, 1kg Availability: In stock
Storage and Shipping
Store in a cool & dry place, keep away from strong light and heat.
References
[1]. Xing S, et al. Sophocarpine inhibits the progression of glioblastoma via PTEN/PI3K/Akt signaling pathway. American Journal of Cancer Research. 2024 Aug 25;14(8):3757-3772.
[2]. Wang Q, et al. Sophocarpine Inhibits Tumorgenesis of Colorectal Cancer via Downregulation of MEK/ERK/VEGF Pathway. Biological & Pharmaceutical Bulletin. 2019 Nov 1;42(11):1830-1838.
[3]. Gao Y, et al. Anti-inflammatory effects of sophocarpine in LPS-induced RAW 264.7 cells via NF-κB and MAPKs signaling pathways. Toxicology in Vitro. 2012 Feb;26(1):1-6.
[4]. Zhang HJ, et al. Sophocarpine alleviates doxorubicin-induced heart injury by suppressing oxidative stress and apoptosis. Scientific Reports. 2024 Jan 3;14(1):428.
[2]. Wang Q, et al. Sophocarpine Inhibits Tumorgenesis of Colorectal Cancer via Downregulation of MEK/ERK/VEGF Pathway. Biological & Pharmaceutical Bulletin. 2019 Nov 1;42(11):1830-1838.
[3]. Gao Y, et al. Anti-inflammatory effects of sophocarpine in LPS-induced RAW 264.7 cells via NF-κB and MAPKs signaling pathways. Toxicology in Vitro. 2012 Feb;26(1):1-6.
[4]. Zhang HJ, et al. Sophocarpine alleviates doxorubicin-induced heart injury by suppressing oxidative stress and apoptosis. Scientific Reports. 2024 Jan 3;14(1):428.
Disclaimer
This product is intended solely for scientific research or regulatory filing purposes. We do not provide products or services to individuals, please strictly comply with all applicable laws, regulations, and the committed use. Use for any other purpose is strictly prohibited.
Related Products
AKA-373
Abietic acid
CAS No.:514-10-3
MF:C20H30O2
AKA-372
Dipexion™ Fmoc-Val-Ser(psi(Me,Me)pro)-OH
CAS No.:186023-49-4
MF:C26H30N2O6
AKA-371
Dipexion™ Fmoc-Gly-Ser(psi(Me,Me)pro)-OH
CAS No.:1095952-22-9
MF:C23H24N2O6
AKA-370
Oxymatrine
CAS No.:16837-52-8
MF:C15H24N2O2
AKA-369
Matrine
CAS No.:519-02-8
MF:C15H24N2O
AKA-368
Dipexion™ Fmoc-Lys（Boc）-Thr[PSI(Me,Me)Pro]-OH
CAS No.:911838-56-7
MF:C33H43N3O8
AKA-367
Dipexion™ Fmoc-Leu-Ser[PSI(Me,Me)Pro]-OH
CAS No.:339531-50-9
MF:C27H32N2O6
AKA-366
Dipexion™ Fmoc-Ser(tBu)-Thr[PSI(Me,Me)Pro]-OH
CAS No.:1266350-99-5
MF:C29H36N2O7
AKA-365
Dipexion™ Fmoc-Glu(OtBu)-Thr[PSI(Me,Me)Pro]-OH
CAS No.:957780-56-2
MF:C31H38N2O8
AKA-364
Dipexion™ Fmoc-Lys（Boc）-Ser[PSI(Me,Me)Pro]-OH
CAS No.:957780-54-0
MF:C32H41N3O8
* Some statements have not been evaluated by national authorities. * Some products are not intended to diagnose, treat, cure, or prevent any disease. * For literature supporting, please contact us directly.
